Compile Data Set for Download or QSAR
maximum 50k data
Found 879 of ec50 for Serotonin (5-HT) receptor
having polymerids = 2152,3427,3428,3737,49000035,49000077,49000089,49000102,49000109,6548,7150,8334 and
complexids = 50004311,50009873
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054973(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(3-{2-[3-...)
Affinity DataEC50:  0.0900nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataEC50:  0.100nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataEC50:  0.100nMAssay Description:Agonist induced [35S]-GTP-gammaS, binding in CHO cells expressing 5-HT 1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054985(Biphenyl-4,4'-disulfonic acid bis-({6-[3-(2-amino-...)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50456128(CHEMBL4215329)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50327872((1-Butylpiperidin-4-yl)methyl 4-Amino-2-methoxyben...)
Affinity DataEC50:  0.178nMAssay Description:Agonist activity at 5HT4 receptor expressed in HEK293/L9 cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054979(2-{5-[2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]...)
Affinity DataEC50:  0.190nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.200nMAssay Description:Partial agonist activity at human 5HT4D receptor expressed in HEK293 cells assessed as cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074205(CHEMBL161176 | N-(3-{4-[3-(5-[1,2,4]Triazol-4-yl-1...)
Affinity DataEC50:  0.200nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060440(3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]tr...)
Affinity DataEC50:  0.200nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074188(2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.200nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077814(3-{3-[4-Fluoro-4-(2-trifluoromethyl-benzyl)-piperi...)
Affinity DataEC50:  0.200nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054987(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-{2-[3-...)
Affinity DataEC50:  0.220nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataEC50:  0.220nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataEC50:  0.240nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at human 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at 5-HT4E receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054980(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(1'-{2-[3...)
Affinity DataEC50:  0.260nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054986(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-{2-[3-...)
Affinity DataEC50:  0.280nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054981(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[3-...)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50456146(CHEMBL4206847)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50456135(CHEMBL4217381)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136469(4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...)
Affinity DataEC50:  0.300nMAssay Description:Ability to inhibit foskolin-stimulated adenylate cyclase activity in Chinese hamster ovary (CHO) stable cell lines expressing human 5-hydroxytryptami...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074202(3-{3-[4-(2-Phenyl-propyl)-piperazin-1-yl]-propyl}-...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074206(3-[3-(4-Pyridin-3-ylmethyl-piperazin-1-yl)-propyl]...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074194(2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074203(3-[3-(4-Furan-3-ylmethyl-piperazin-1-yl)-propyl]-5...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074198(3-[3-(4-Pyridin-2-ylmethyl-piperazin-1-yl)-propyl]...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074186(3-{3-[4-(4-Fluoro-benzyl)-piperazin-1-yl]-propyl}-...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074178((1-Methyl-1-phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]tria...)
Affinity DataEC50:  0.300nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human 5HT4B receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398590(CHEMBL2179583)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at human 5HT4A receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50414722(CHEMBL539713)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054988(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-[4-(4-{2-...)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataEC50:  0.400nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataEC50:  0.400nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398599(CHEMBL2179580)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human 5HT4D receptor expressed in HEK293 cells assessed as cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065417(3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-...)
Affinity DataEC50:  0.400nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50456136(CHEMBL4211044)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054976(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-{2-[3-(2-...)
Affinity DataEC50:  0.440nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataEC50:  0.450nMAssay Description:Measurement of agonist induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataEC50:  0.450nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1Dbeta receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at human 5HT4A receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50499468(CHEMBL3741376)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065417(3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-...)
Affinity DataEC50:  0.5nMAssay Description:Agonist induced [35S]-GTP-gammaS, binding in CHO cells expressing 5-HT 1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074201(3-[3-(4-Furan-2-ylmethyl-piperazin-1-yl)-propyl]-5...)
Affinity DataEC50:  0.5nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataEC50:  0.5nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083144(CHEMBL146285 | [1-(4-Fluoro-phenyl)-ethyl]-{1-[3-(...)
Affinity DataEC50:  0.5nMAssay Description:Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50080890(3-((2R,3aR,6aR)-5-Benzyl-1-methyl-octahydro-pyrrol...)
Affinity DataEC50:  0.5nMAssay Description:Measurement of agonist induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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